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PGD (Preimplantation Genetic Diagnosis)

PGD (Preimplantation Genetic Diagnosis)

PGD is a genetic screening test conducted to select the best embryo from an IVF procedure before the implantation phase. PGD is one of the best techniques available at Rathimed Fertility Centre to assist our fertility specialists in identifying and avoiding passage of serious genetic diseases, allowing your baby to have a healthy start. The test ensures that the embryo with no genetic defect or disease is transferred and implanted for development that may lead to disease during or after a child’s birth. Pre-implantation Genetic Diagnosis is recommended for patients who are carriers of chromosomal

data

abnormalities or any specific genetic diseases. Embryo developed with an abnormal chromosome is at a higher risk for getting miscarriages. The Preimplantation Genetic Diagnosis completely eliminates the chances for carrying a genetic disorder from parents to their off-springs.

PGD procedure

During the IVF procedure, the egg and sperms are mixed to fuse and fertilize to develop an embryo. The embryo rapidly multiples and reaches the multi- celled stage. Once the embryo is multi-celled, few sample cells are collected from the embryo through biopsy and the PGD test is conducted.

The biopsy process does not harm the embryo and is performed in two ways:

  • A biopsy on 3rd day of fertilization performed on polar bodies of cleavage stage embryos, collecting a single cell from the embryo
  • A biopsy on 5th, 6th or 7th day at Trophectoderm stage, collecting a few cells each from the embryos

The embryos are preserved until the results are generated. Once the results are confirmed, the embryo is transferred into the uterine cavity for implantation. PGD test decreases the risk of having a child who carries a genetic abnormality.

PGD help identify numerous genetic disorders including Cystic Fibrosis, Fragile X, Myotonic Dystrophy, Thalasaemia and Tay Sachs.

Who is a good candidate for PGD?

Any partner couples who have a known genetic disorder are suggested to have a pre implantation diagnosis test to ensure that the abnormality is not passed into next generation and to enhance the chances for implantation. Other circumstances that recommend a PGD test include:

  • Couples who are experiencing repeat pregnancy loss and implantation failure
  • Couples who already have one child with a genetic disorder

Rathimed Fertility Centre increases the likelihood of giving birth to a healthy child in conjunction with In-Vitro Fertilization to help choose the healthiest embryos for implantation and development. Our centre has an exceptional profile history in providing infertility treatment care and support with excellent medical infrastructure and modern utilities. We provide customized treatment plans for couples with multiple fertility treatment options to conceive. We possess a team of fertility specialists to offer an accurate diagnosis, to choose the right treatment modality for an individual case and help them to conceive sooner. To know more about Preimplantation Genetic Diagnosis or for any queries related to infertility treatments, contact us.

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